Sandbox Reserved 969: Difference between revisions

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====Closed Conformation====
====Closed Conformation====


In the closed conformation, inner helices are near and straight. There is a subsequent '''bundle crossing''' formed by interactions between C-terminal residues. In the region just above the bundle crossing, <scene name='60/604488/Phe_92/1'>Phe92</scene> from each inner helix forms contacts with a '''hydrophobic patch''' on the opposite face of Phe92 from the neighboring inner helix formed by Val91, Phe94, Ile95 and Leu98. <ref> PMID: 19098917</ref>
In the closed conformation, inner helices are near and straight. There is a subsequent '''bundle crossing''' formed by interactions between C-terminal residues. In the region just above the bundle crossing, <scene name='60/604488/Phe_92/2'>Phe 92</scene> from each inner helix forms contacts with a '''hydrophobic patch''' on the opposite face of Phe92 from the neighboring inner helix formed by Val91, Phe94, Ile95 and Leu98. <ref> PMID: 19098917</ref>