4xba: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Hnt3==

~~The entry~~ 4xba is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xba]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XBA FirstGlance]. <br>

~~Authors~~: ~~Jacewicz~~, A., ~~Chauleau~~, M., ~~Shuman~~, S.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xba RCSB], [http://www.ebi.ac.uk/pdbsum/4xba PDBsum]</span></td></tr>

~~Description: Hnt3~~

</table>

[[Category: ~~Unreleased Structures~~]]

== Function ==

[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).

__TOC__

</StructureSection>

[[Category: Chauleau, M]]

[[Category: Jacewicz, A]]

[[Category: Shuman, S]]

[[Category: ~~Chauleau, M~~]]

[[Category: Gmp]]

[[Category: Hydrolase]]

[[Category: Nucleotidyl transferase]]

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-'''Unreleased structure'''
+==Hnt3==
+<StructureSection load='4xba' size='340' side='right' caption='[[4xba]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
-The entry 4xba is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xba]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XBA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XBA FirstGlance]. <br>
-Authors: Jacewicz, A., Chauleau, M., Shuman, S.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=GMP:GUANOSINE'>GMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xba OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xba RCSB], [http://www.ebi.ac.uk/pdbsum/4xba PDBsum]</span></td></tr>
-Description: Hnt3
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
+[[http://www.uniprot.org/uniprot/APTX_SCHPO APTX_SCHPO]] DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Chauleau, M]]
 [[Category: Jacewicz, A]]
 [[Category: Shuman, S]]
-[[Category: Chauleau, M]]
+[[Category: Gmp]]
+[[Category: Hydrolase]]
+[[Category: Nucleotidyl transferase]]