4xdj: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)==

~~The entry~~ 4xdj is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xdj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDJ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XDJ FirstGlance].

~~Authors~~: ~~Pike, A.C~~.W.~~, Dong, Y~~.Y.~~, Mackenzie, A~~.~~, Mukhopadhyay, S~~.~~, Arrowsmith, C~~.H.~~, Edwards, A.M~~., ~~Bountra~~, ~~C., Burgess~~-~~Brown~~, ~~N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>, <scene name='pdbligand=TRD:TRIDECANE'>TRD</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4bw5|4bw5]]</td></tr>

~~Description~~:

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xdj RCSB], [http://www.ebi.ac.uk/pdbsum/4xdj PDBsum]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

[~~[Category~~: ~~Pike, A~~.C.W]]

== Function ==

[~~[Category~~: ~~Burgess~~-~~Brown~~, N.A]]

[[http://www.uniprot.org/uniprot/KCNKA_HUMAN KCNKA_HUMAN]] Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.

[[~~Category~~: ~~Mukhopadhyay, S~~]]

__TOC__

[[Category: ~~Carpenter~~, ~~E.P~~]]

</StructureSection>

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Burgess-Brown, N A]]

[[Category: Carpenter, E P]]

[[Category: Dong, Y Y]]

[[Category: Edwards, A M]]

[[Category: Mackenzie, A]]

[[Category: ~~Arrowsmith~~, C.H]]

[[Category: Mukhopadhyay, S]]

[[Category: ~~Dong, Y.Y~~]]

[[Category: Pike, A C.W]]

[[Category: ~~Edwards, A.M~~]]

[[Category: Structural genomic]]

[[Category: ~~Structural Genomics Consortium (~~Sgc)]]

[[Category: K2p]]

[[Category: Membrane protein]]

[[Category: Outward rectification]]

[[Category: Sgc]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)==
+<StructureSection load='4xdj' size='340' side='right' caption='[[4xdj]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
-The entry 4xdj is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xdj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XDJ FirstGlance]. <br>
-Authors: Pike, A.C.W., Dong, Y.Y., Mackenzie, A., Mukhopadhyay, S., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Burgess-Brown, N.A., Carpenter, E.P., Structural Genomics Consortium (SGC)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene>, <scene name='pdbligand=TRD:TRIDECANE'>TRD</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bw5|4bw5]]</td></tr>
-Description:
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xdj RCSB], [http://www.ebi.ac.uk/pdbsum/4xdj PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Pike, A.C.W]]
+== Function ==
-[[Category: Burgess-Brown, N.A]]
+[[http://www.uniprot.org/uniprot/KCNKA_HUMAN KCNKA_HUMAN]] Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
-[[Category: Mukhopadhyay, S]]
+__TOC__
-[[Category: Carpenter, E.P]]
+</StructureSection>
+[[Category: Arrowsmith, C H]]
 [[Category: Bountra, C]]
+[[Category: Burgess-Brown, N A]]
+[[Category: Carpenter, E P]]
+[[Category: Dong, Y Y]]
+[[Category: Edwards, A M]]
 [[Category: Mackenzie, A]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Mukhopadhyay, S]]
-[[Category: Dong, Y.Y]]
+[[Category: Pike, A C.W]]
-[[Category: Edwards, A.M]]
+[[Category: Structural genomic]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: K2p]]
+[[Category: Membrane protein]]
+[[Category: Outward rectification]]
+[[Category: Sgc]]
+[[Category: Transport protein]]