2jh0: Difference between revisions

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|PDB= 2jh0 |SIZE=350|CAPTION= <scene name='initialview01'>2jh0</scene>, resolution 1.70&Aring;
|PDB= 2jh0 |SIZE=350|CAPTION= <scene name='initialview01'>2jh0</scene>, resolution 1.70&Aring;
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+D'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:Na+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=701:(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE'>701</scene>
|LIGAND= <scene name='pdbligand=701:(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE'>701</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jh0 OCA], [http://www.ebi.ac.uk/pdbsum/2jh0 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jh0 RCSB]</span>
}}
}}


'''HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.'''
'''HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.'''


==Disease==
Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]


==About this Structure==
==About this Structure==
Line 27: Line 27:
[[Category: Watson, N S.]]
[[Category: Watson, N S.]]
[[Category: Young, R J.]]
[[Category: Young, R J.]]
[[Category: 701]]
[[Category: CA]]
[[Category: NA]]
[[Category: acute phase]]
[[Category: acute phase]]
[[Category: blood coagulation]]
[[Category: blood coagulation]]
Line 48: Line 45:
[[Category: zymogen]]
[[Category: zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:48 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:05 2008''

Revision as of 00:58, 31 March 2008

File:2jh0.jpg


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2jh0, resolution 1.70Å
Sites: AC1
Ligands: 701, CA, NA, TYS
Activity: Thrombin, with EC number 3.4.21.5
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



HUMAN THROMBIN HIRUGEN INHIBITOR COMPLEX.


About this Structure

2JH0 is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 03:58:05 2008

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