2wpj: Difference between revisions
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==factor IXa superactive triple mutant, NaCl-soaked== | ==factor IXa superactive triple mutant, NaCl-soaked== | ||
<StructureSection load='2wpj' size='340' side='right' caption='[[2wpj]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='2wpj' size='340' side='right' caption='[[2wpj]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wpj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2wpj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPJ FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DPN:D-PHENYLALANINE'>DPN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1edm|1edm]], [[1cfh|1cfh]], [[2wpm|2wpm]], [[1mgx|1mgx]], [[2wpi|2wpi]], [[2wpl|2wpl]], [[1cfi|1cfi]], [[2wph|2wph]], [[1ixa|1ixa]], [[2wpk|2wpk]], [[1rfn|1rfn]], [[1nl0|1nl0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1edm|1edm]], [[1cfh|1cfh]], [[2wpm|2wpm]], [[1mgx|1mgx]], [[2wpi|2wpi]], [[2wpl|2wpl]], [[1cfi|1cfi]], [[2wph|2wph]], [[1ixa|1ixa]], [[2wpk|2wpk]], [[1rfn|1rfn]], [[1nl0|1nl0]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_IXa Coagulation factor IXa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.22 3.4.21.22] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_IXa Coagulation factor IXa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.22 3.4.21.22] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wpj RCSB], [http://www.ebi.ac.uk/pdbsum/2wpj PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpj OCA], [http://pdbe.org/2wpj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpj RCSB], [http://www.ebi.ac.uk/pdbsum/2wpj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wpj ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2wpj" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Coagulation factor IXa]] | [[Category: Coagulation factor IXa]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Brandstetter, H]] | [[Category: Brandstetter, H]] | ||
[[Category: Zogg, T]] | [[Category: Zogg, T]] | ||