4rze: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant==

~~The entry~~ 4rze is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4rze]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZE OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZE FirstGlance].

~~Authors~~: ~~Fengwei~~, L., ~~Xuyang, T~~., ~~Anzhong, L~~.~~, Li, L~~.~~, Yuan, L~~., ~~Hangzi, C~~.~~, Qiao, W~~.~~, Tianwei, L~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4rzf|4rzf]], [[4rzg|4rzg]]</td></tr>

~~Description~~: ~~Crystal Structure Analysis~~ of the ~~NUR77 Ligand Binding Domain, L437W,D594E mutant~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rze OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rze RCSB], [http://www.ebi.ac.uk/pdbsum/4rze PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Anzhong, L]]

[[Category: Fengwei, L]]

~~[[Category: Xuyang, T]]~~

~~[[Category: Yuan, L]]~~

~~[[Category: Anzhong, L]]~~

~~[[Category: Tianwei, L]]~~

[[Category: Hangzi, C]]

[[Category: Li, L]]

[[Category: Qiao, W]]

[[Category: Tianwei, L]]

[[Category: Xuyang, T]]

[[Category: Yuan, L]]

[[Category: Transcription]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant==
+<StructureSection load='4rze' size='340' side='right' caption='[[4rze]], [[Resolution|resolution]] 2.49&Aring;' scene=''>
-The entry 4rze is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rze]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RZE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RZE FirstGlance]. <br>
-Authors: Fengwei, L., Xuyang, T., Anzhong, L., Li, L., Yuan, L., Hangzi, C., Qiao, W., Tianwei, L.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rzf|4rzf]], [[4rzg|4rzg]]</td></tr>
-Description: Crystal Structure Analysis of the NUR77 Ligand Binding Domain, L437W,D594E mutant
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rze OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rze RCSB], [http://www.ebi.ac.uk/pdbsum/4rze PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NR4A1_HUMAN NR4A1_HUMAN]] Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2.<ref>PMID:15466594</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Anzhong, L]]
 [[Category: Fengwei, L]]
-[[Category: Xuyang, T]]
-[[Category: Yuan, L]]
-[[Category: Anzhong, L]]
-[[Category: Tianwei, L]]
 [[Category: Hangzi, C]]
 [[Category: Li, L]]
 [[Category: Qiao, W]]
+[[Category: Tianwei, L]]
+[[Category: Xuyang, T]]
+[[Category: Yuan, L]]
+[[Category: Transcription]]