4xjw: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant==

~~The entry 4xjw is ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4xjw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJW OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJW FirstGlance].

~~Authors: Brear, P.~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </td></tr>

~~Description:~~ Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjw OCA], [http://pdbe.org/4xjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjw RCSB], [http://www.ebi.ac.uk/pdbsum/4xjw PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

__TOC__

</StructureSection>

[[Category: Exo-alpha-sialidase]]

[[Category: Brear, P]]

[[Category: Allosteric inhibitor]]

[[Category: Crystallization artefact]]

[[Category: Drug design]]

[[Category: Glycosidase]]

[[Category: Hydrolase]]

[[Category: Intramolecular trans-sialidase]]

[[Category: Neuraminidase]]

[[Category: Serendipitous allosteric site]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant==
+<StructureSection load='4xjw' size='340' side='right' caption='[[4xjw]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
-The entry 4xjw is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4xjw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XJW FirstGlance]. <br>
-Authors: Brear, P.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=OPX:(1S,3R,4S)-1-[(CYCLOHEXYLAMINO)METHYL]-3,4-DIHYDROXYCYCLOPENTANESULFONIC+ACID'>OPX</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
-Description: Crystal structure of the NanB sialidase from streptococcus pneumoniae in complex with Optactin at pH 7.4 in PBS with DMSO as the cryoprotectant
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjw OCA], [http://pdbe.org/4xjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xjw RCSB], [http://www.ebi.ac.uk/pdbsum/4xjw PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+__TOC__
+</StructureSection>
+[[Category: Exo-alpha-sialidase]]
 [[Category: Brear, P]]
+[[Category: Allosteric inhibitor]]
+[[Category: Crystallization artefact]]
+[[Category: Drug design]]
+[[Category: Glycosidase]]
+[[Category: Hydrolase]]
+[[Category: Intramolecular trans-sialidase]]
+[[Category: Neuraminidase]]
+[[Category: Serendipitous allosteric site]]