4xli: Difference between revisions
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''' | ==Crystal structure of Abl2/Arg kinase in complex with dasatinib== | ||
<StructureSection load='4xli' size='340' side='right' caption='[[4xli]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xli]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XLI FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1N1:N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE'>1N1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xli RCSB], [http://www.ebi.ac.uk/pdbsum/4xli PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Ha, B | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Non-specific protein-tyrosine kinase]] | |||
[[Category: Boggon, T J]] | |||
[[Category: Ha, B H]] | |||
[[Category: Inhibitor]] | |||
[[Category: Kinase]] | |||
[[Category: Transferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 13:21, 1 April 2015
Crystal structure of Abl2/Arg kinase in complex with dasatinib
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