Antimicrobial peptides: Difference between revisions
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==History== | ==History== | ||
Alexander Fleming | The first AMP was discovered by Alexander Fleming about 90 years ago. He recognized the presence of a soluble antimicrobial substance produced by human nasal secretions from a patient suffering from acute coryza. He called it [[Lysozyme]] as it performed lysis to bacterial cells. | ||
Subsequently, he found lysozyme antibacterial activity in various human physiological fluids and tissues of animals, as well as egg whites. | Subsequently, he found lysozyme antibacterial activity in various human physiological fluids and tissues of animals, as well as egg whites. | ||
Natural examples are found in all classes of organisms: animals including humans, invertebrate animals, plants, and fungi. | Natural examples for AMPs are found in all classes of organisms: animals including humans, invertebrate animals, plants, and fungi. | ||
So far more than 1,200 types of peptides with antimicrobial activity have been isolated from various cells and tissues. | So far more than 1,200 types of peptides with antimicrobial activity have been isolated from various cells and tissues. | ||
