2xcf: Difference between revisions
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==CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR== | ==CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR== | ||
<StructureSection load='2xcf' size='340' side='right' caption='[[2xcf]], [[Resolution|resolution]] 2.48Å' scene=''> | <StructureSection load='2xcf' size='340' side='right' caption='[[2xcf]], [[Resolution|resolution]] 2.48Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2xcf]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/9hepc 9hepc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XCF FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBQ:CYCLOPENTYL+N-[(2S)-1-[(2S,4R)-2-[[(4R)-8-HYDROXY-1,6,10-TRIOXA-5$L^{4}-BORASPIRO[4.5]DECAN-4-YL]CARBAMOYL]-4-ISOQUINOLIN-1-YLOXY-PYRROLIDIN-1-YL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE'>BBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BBQ:CYCLOPENTYL+N-[(2S)-1-[(2S,4R)-2-[[(4R)-8-HYDROXY-1,6,10-TRIOXA-5$L^{4}-BORASPIRO[4.5]DECAN-4-YL]CARBAMOYL]-4-ISOQUINOLIN-1-YLOXY-PYRROLIDIN-1-YL]-3,3-DIMETHYL-1-OXO-BUTAN-2-YL]CARBAMATE'>BBQ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xcf RCSB], [http://www.ebi.ac.uk/pdbsum/2xcf PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xcf OCA], [http://pdbe.org/2xcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xcf RCSB], [http://www.ebi.ac.uk/pdbsum/2xcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xcf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2xcf" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Baker, S J]] | [[Category: Baker, S J]] | ||
[[Category: Ding, C Z]] | [[Category: Ding, C Z]] | ||
Revision as of 08:10, 11 August 2016
CRYSTAL STRUCTURE OF HCV NS3 PROTEASE WITH A BORONATE INHIBITOR
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Baker, S J
- Ding, C Z
- Edge, C M
- Ellis, M
- Fan, D
- Grimes, R M
- Hubbard, J A
- Jarvest, R L
- Kazmierski, W M
- Lazarides, L X
- Li, Q
- Li, X
- Liao, L
- Liu, Y
- Mcdowell, B
- Mordaunt, J E
- Nassau, P
- Ni, Z J
- Pennicott, L E
- Plattner, J J
- Qian, X
- Rowland, P
- Skarzynski, T J
- Slater, M J
- Smith, G K
- Somers, D O
- Thommes, P
- White, G V
- Wright, J
- Wright, L L
- Zhang, Y K
- Zhou, Y
- Zou, W
- Boronate inhibitor
- Hydrolase
- Protease
- Viral reproduction
