2p6x: Difference between revisions

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|PDB= 2p6x |SIZE=350|CAPTION= <scene name='initialview01'>2p6x</scene>, resolution 1.90&Aring;
|PDB= 2p6x |SIZE=350|CAPTION= <scene name='initialview01'>2p6x</scene>, resolution 1.90&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
|GENE= PTPN22, PTPN8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= PTPN22, PTPN8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2oc3|2OC3]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2p6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p6x OCA], [http://www.ebi.ac.uk/pdbsum/2p6x PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2p6x RCSB]</span>
}}
}}


'''Crystal structure of human tyrosine phosphatase PTPN22'''
'''Crystal structure of human tyrosine phosphatase PTPN22'''


==Disease==
Known diseases associated with this structure: Diabetes mellitus, insulin-dependent, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Rheumatoid arthritis, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]], Systemic lupus erythematosus, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600716 600716]]


==About this Structure==
==About this Structure==
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[[Category: Uppenberg, J.]]
[[Category: Uppenberg, J.]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J.]]
[[Category: CL]]
[[Category: EDO]]
[[Category: lymphoid phosphatase]]
[[Category: lymphoid phosphatase]]
[[Category: lyp]]
[[Category: lyp]]
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[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:09:35 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:31:10 2008''

Revision as of 01:31, 31 March 2008

File:2p6x.jpg


Drag the structure with the mouse to rotate
2p6x, resolution 1.90Å
Ligands: CL, EDO
Gene: PTPN22, PTPN8 (Homo sapiens)
Activity: Protein-tyrosine-phosphatase, with EC number 3.1.3.48
Related: 2OC3


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal structure of human tyrosine phosphatase PTPN22


About this Structure

2P6X is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Mon Mar 31 04:31:10 2008

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