2pio: Difference between revisions

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|PDB= 2pio |SIZE=350|CAPTION= <scene name='initialview01'>2pio</scene>, resolution 2.03&Aring;
|PDB= 2pio |SIZE=350|CAPTION= <scene name='initialview01'>2pio</scene>, resolution 2.03&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene> and <scene name='pdbligand=2MI:2-METHYL-1H-INDOLE'>2MI</scene>
|LIGAND= <scene name='pdbligand=2MI:2-METHYL-1H-INDOLE'>2MI</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2pin|2PIN]], [[2pip|2PIP]], [[2piq|2PIQ]], [[2pir|2PIR]], [[2pit|2PIT]], [[2piu|2PIU]], [[2piv|2PIV]], [[2piw|2PIW]], [[2pix|2PIX]], [[2pkl|2PKL]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pio OCA], [http://www.ebi.ac.uk/pdbsum/2pio PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pio RCSB]</span>
}}
}}


'''Androgen receptor LBD with small molecule'''
'''Androgen receptor LBD with small molecule'''


==Disease==
Known diseases associated with this structure: Androgen insensitivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Breast cancer, male, with Reifenstein syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Hypospadias, perineal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Spinal and bulbar muscular atrophy of Kennedy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]]


==About this Structure==
==About this Structure==
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[[Category: Guy, R K.]]
[[Category: Guy, R K.]]
[[Category: Webb, P.]]
[[Category: Webb, P.]]
[[Category: 2MI]]
[[Category: DHT]]
[[Category: SO4]]
[[Category: androgen receptor ligand binding domain]]
[[Category: androgen receptor ligand binding domain]]
[[Category: hormone receptor]]
[[Category: hormone receptor]]
[[Category: inhibitors coactivator binding af-2 pocket]]
[[Category: inhibitors coactivator binding af-2 pocket]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:36:25 2008''
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