2pit: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 4: Line 4:
|PDB= 2pit |SIZE=350|CAPTION= <scene name='initialview01'>2pit</scene>, resolution 1.76&Aring;
|PDB= 2pit |SIZE=350|CAPTION= <scene name='initialview01'>2pit</scene>, resolution 1.76&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene> and <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC ACID'>4HY</scene>
|LIGAND= <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC+ACID'>4HY</scene>, <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= AR, DHTR, NR3C4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2pin|2PIN]], [[2pio|2PIO]], [[2pip|2PIP]], [[2piq|2PIQ]], [[2pir|2PIR]], [[2piu|2PIU]], [[2piv|2PIV]], [[2piw|2PIW]], [[2pix|2PIX]], [[2pkl|2PKL]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pit OCA], [http://www.ebi.ac.uk/pdbsum/2pit PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pit RCSB]</span>
}}
}}


'''Androgen receptor LBD with small molecule'''
'''Androgen receptor LBD with small molecule'''


==Disease==
Known diseases associated with this structure: Androgen insensitivity OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Breast cancer, male, with Reifenstein syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Hypospadias, perineal OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Prostate cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]], Spinal and bulbar muscular atrophy of Kennedy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=313700 313700]]


==About this Structure==
==About this Structure==
Line 25: Line 25:
[[Category: Guy, R K.]]
[[Category: Guy, R K.]]
[[Category: Webb, P.]]
[[Category: Webb, P.]]
[[Category: 4HY]]
[[Category: DHT]]
[[Category: SO4]]
[[Category: androgen receptor coactivator binding inhibitors af-2]]
[[Category: androgen receptor coactivator binding inhibitors af-2]]
[[Category: hormone receptor]]
[[Category: hormone receptor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:13:30 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:36:28 2008''
Retrieved from "https://proteopedia.org/2pit"