4xnv: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
''' | ==The human P2Y1 receptor in complex with BPTU== | ||
<StructureSection load='4xnv' size='340' side='right' caption='[[4xnv]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4xnv]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XNV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XNV FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=BUR:1-[2-(2-TERT-BUTYLPHENOXY)PYRIDIN-3-YL]-3-[4-(TRIFLUOROMETHOXY)PHENYL]UREA'>BUR</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xnw|4xnw]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xnv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xnv RCSB], [http://www.ebi.ac.uk/pdbsum/4xnv PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/P2RY1_HUMAN P2RY1_HUMAN]] Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.<ref>PMID:9442040</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Gao, Z]] | |||
[[Category: Han, G W]] | |||
[[Category: Jacobson, K]] | |||
[[Category: Stevens, R]] | |||
[[Category: Wu, B]] | [[Category: Wu, B]] | ||
[[Category: Zhang, D]] | [[Category: Zhang, D]] | ||
[[Category: Zhao, Q]] | [[Category: Zhao, Q]] | ||
[[Category: G protein coupled receptor]] | |||
[[Category: Human p2y1 receptor]] | |||
[[Category: Inhibitor complex]] | |||
[[Category: Membrane protein]] | |||
[[Category: Platelet activation]] | |||
[[Category: Transport protein-inhibitor complex]] | |||
Revision as of 13:22, 1 April 2015
The human P2Y1 receptor in complex with BPTU
| ||||||||||||
