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| ==Metal Ion Binding at the Catalytic Site Induces Widespread Changes in a Sequence-specific Protein-DNA Complex==
| | #REDIRECT [[5hlk]] This PDB entry is obsolete and replaced by 5hlk |
| <StructureSection load='4orj' size='340' side='right' caption='[[4orj]], [[Resolution|resolution]] 2.10Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[4orj]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ORJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ORJ FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=LU:LUTETIUM+(III)+ION'>LU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4orj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4orj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4orj RCSB], [http://www.ebi.ac.uk/pdbsum/4orj PDBsum]</span></td></tr>
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| </table>
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| == Function ==
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| [[http://www.uniprot.org/uniprot/T2E5_ECOLX T2E5_ECOLX]] Recognizes the double-stranded sequence GATATC and cleaves after T-3.
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| __TOC__
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| </StructureSection>
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| [[Category: Type II site-specific deoxyribonuclease]]
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| [[Category: Jen-Jacobson, L]]
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| [[Category: Kehr, A D]]
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| [[Category: Kurpiewski, M R]]
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| [[Category: Rule, G S]]
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| [[Category: Sangani, S S]]
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| [[Category: Sinha, K]]
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| [[Category: Hydrolase-dna complex]]
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| [[Category: Restriction endonuclease]]
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