5ahl: Difference between revisions
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''' | ==Apo-form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa== | ||
<StructureSection load='5ahl' size='340' side='right' caption='[[5ahl]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5ahl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AHL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ahm|5ahm]], [[5ahn|5ahn]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ahl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ahl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ahl RCSB], [http://www.ebi.ac.uk/pdbsum/5ahl PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: IMP dehydrogenase]] | |||
[[Category: Alexandre, T]] | |||
[[Category: Gelin, M]] | |||
[[Category: Haouz, A]] | |||
[[Category: Labesse, G]] | [[Category: Labesse, G]] | ||
[[Category: Munier-Lehmann, H]] | [[Category: Munier-Lehmann, H]] | ||
[[Category: | [[Category: Allosteric regu nucleotide metabolism]] | ||
[[Category: | [[Category: Cbs module]] | ||
[[Category: | [[Category: Deletion mutant]] | ||
[[Category: Oxidoreductase]] | |||
Revision as of 13:39, 15 July 2015
Apo-form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa
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