4ycg: Difference between revisions
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''' | ==Pro-bone morphogenetic protein 9== | ||
<StructureSection load='4ycg' size='340' side='right' caption='[[4ycg]], [[Resolution|resolution]] 3.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ycg]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YCG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YCG FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ycg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ycg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ycg RCSB], [http://www.ebi.ac.uk/pdbsum/4ycg PDBsum]</span></td></tr> | |||
</table> | |||
[[Category: | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/GDF2_MOUSE GDF2_MOUSE]] Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.<ref>PMID:23300529</ref> [[http://www.uniprot.org/uniprot/GDF2_HUMAN GDF2_HUMAN]] Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks.<ref>PMID:18309101</ref> <ref>PMID:22799562</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Brown, C T]] | |||
[[Category: Gao, Y]] | |||
[[Category: Le, V]] | |||
[[Category: Mi, L Z]] | |||
[[Category: Springer, T A]] | |||
[[Category: Tian, Y]] | |||
[[Category: Walz, T]] | |||
[[Category: Cytokine]] | |||
[[Category: Morphogen]] | |||
[[Category: Pro-bmp complex]] | |||
[[Category: Transforming growth factor-beta family]] | |||
