Theoretical esterases: Difference between revisions

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== Background ==
== Background ==


''De Novo'' protein design and synthesis has been a goal of Biochemistry for decades and has wide sweeping implications in many fields. The advent of computers has given rise to computer programs such as RosettaMatch which are capable of identifying sequences compatible with given protein skeletons.  In August of 2012, the Richter Lab and collaborators published an attempted to design an esterase from a theoretically functional protein backbone.  This article is a summary of their contribution to the field of ''De Novo'' esterase design.   
''De Novo'' protein design and synthesis has been a goal of Biochemistry for decades and has wide sweeping implications in many fields. The advent of computers has given rise to computer programs such as RosettaMatch which are capable of identifying sequences compatible with given protein skeletons.  In August of 2012, the Richter Lab and collaborators published an attempted to design an esterase from a theoretically functional protein backbone.  This article is a summary of their contribution to the field of ''de Novo'' esterase design.   


== Design ==
== Design ==