Theoretical esterases: Difference between revisions
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None of the proposed de novo structures were able to create a functional, efficient esterase as designed. While it is worth being appreciative of the fact that the Richter lab and collaborators were able to get as close as they were, both the technology of protein structure predication and our own knowledge of protein folding mechanisms must increase before we can reliably design proteins from the bottom up. | None of the proposed de novo structures were able to create a functional, efficient esterase as designed. While it is worth being appreciative of the fact that the Richter lab and collaborators were able to get as close as they were, both the technology of protein structure predication and our own knowledge of protein folding mechanisms must increase before we can reliably design proteins from the bottom up. | ||
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== Structural highlights == | == Structural highlights == | ||
