Sandbox Reserved 992: Difference between revisions

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{{Sandbox_gvsu_chm463}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
{{Sandbox_gvsu_chm463}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
{{GNF_Protein_box/sandbox
| name = PBB/9353
| Name = Slit homolog 2 (Drosophila)
| image = Protein_SLIT2_PDB_2V70.png
| image_source = Rendering based on [[Protein_Data_Bank | PDB]] {{PDB2|2V70}}.
| PDB = {{PDB2|2V70}}, {{PDB2|2V9S}}, {{PDB2|2V9T}}, {{PDB2|2WFH}}
| HGNCid = 11086
| MGIid = 1315205
| Symbol = SLIT2
| AltSymbols =; FLJ14420; SLIL3; Slit-2
| OMIM = 603746
| ECnumber =
| Homologene = 3516
| GeneAtlas_image1 = PBB_GE_SLIT2_209897_s_at_tn.png
| GeneAtlas_image2 =
| GeneAtlas_image3 =
| Protein_domain_image =
| Function = {{GNF_GO|id=GO:0005095 |text = GTPase inhibitor activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008201 |text = heparin binding}} {{GNF_GO|id=GO:0042803 |text = protein homodimerization activity}} {{GNF_GO|id=GO:0043237 |text = laminin-1 binding}} {{GNF_GO|id=GO:0043394 |text = proteoglycan binding}} {{GNF_GO|id=GO:0048495 |text = Roundabout binding}}
| Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}} {{GNF_GO|id=GO:0009986 |text = cell surface}} {{GNF_GO|id=GO:0016020 |text = membrane}}
| Process = {{GNF_GO|id=GO:0001657 |text = ureteric bud development}} {{GNF_GO|id=GO:0001933 |text = negative regulation of protein phosphorylation}} {{GNF_GO|id=GO:0002042 |text = cell migration involved in sprouting angiogenesis}} {{GNF_GO|id=GO:0002689 |text = negative regulation of leukocyte chemotaxis}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0007411 |text = axon guidance}} {{GNF_GO|id=GO:0008045 |text = motor axon guidance}} {{GNF_GO|id=GO:0010593 |text = negative regulation of lamellipodium assembly}} {{GNF_GO|id=GO:0010596 |text = negative regulation of endothelial cell migration}} {{GNF_GO|id=GO:0014912 |text = negative regulation of smooth muscle cell migration}} {{GNF_GO|id=GO:0021834 |text = chemorepulsion involved in embryonic olfactory bulb interneuron migration}} {{GNF_GO|id=GO:0021836 |text = chemorepulsion involved in postnatal olfactory bulb interneuron migration}} {{GNF_GO|id=GO:0021972 |text = corticospinal neuron axon guidance through spinal cord}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}} {{GNF_GO|id=GO:0030308 |text = negative regulation of cell growth}} {{GNF_GO|id=GO:0030336 |text = negative regulation of cell migration}} {{GNF_GO|id=GO:0030336 |text = negative regulation of cell migration}} {{GNF_GO|id=GO:0030837 |text = negative regulation of actin filament polymerization}} {{GNF_GO|id=GO:0031290 |text = retinal ganglion cell axon guidance}} {{GNF_GO|id=GO:0032870 |text = cellular response to hormone stimulus}} {{GNF_GO|id=GO:0035385 |text = Roundabout signaling pathway}} {{GNF_GO|id=GO:0043065 |text = positive regulation of apoptosis}} {{GNF_GO|id=GO:0043116 |text = negative regulation of vascular permeability}} {{GNF_GO|id=GO:0048754 |text = branching morphogenesis of a tube}} {{GNF_GO|id=GO:0048754 |text = branching morphogenesis of a tube}} {{GNF_GO|id=GO:0048846 |text = axon extension involved in axon guidance}} {{GNF_GO|id=GO:0050772 |text = positive regulation of axonogenesis}} {{GNF_GO|id=GO:0050919 |text = negative chemotaxis}} {{GNF_GO|id=GO:0050919 |text = negative chemotaxis}} {{GNF_GO|id=GO:0050929 |text = induction of negative chemotaxis}} {{GNF_GO|id=GO:0051058 |text = negative regulation of small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0051414 |text = response to cortisol stimulus}} {{GNF_GO|id=GO:0061364 |text = apoptosis involved in luteolysis}} {{GNF_GO|id=GO:0070100 |text = negative regulation of chemokine-mediated signaling pathway}} {{GNF_GO|id=GO:0071504 |text = cellular response to heparin}} {{GNF_GO|id=GO:0071672 |text = negative regulation of smooth muscle cell chemotaxis}} {{GNF_GO|id=GO:0071676 |text = negative regulation of mononuclear cell migration}} {{GNF_GO|id=GO:0090024 |text = negative regulation of neutrophil chemotaxis}} {{GNF_GO|id=GO:0090260 |text = negative regulation of retinal ganglion cell axon guidance}} {{GNF_GO|id=GO:0090288 |text = negative regulation of cellular response to growth factor stimulus}}
| Hs_EntrezGene = 9353
| Hs_Ensembl = ENSG00000145147
| Hs_RefseqmRNA = NM_004787
| Hs_RefseqProtein = NP_004778
| Hs_GenLoc_db = hg19
| Hs_GenLoc_chr = 4
| Hs_GenLoc_start = 20254883
| Hs_GenLoc_end = 20622184
| Hs_Uniprot = O94813
| Mm_EntrezGene = 20563
| Mm_Ensembl = ENSMUSG00000031558
| Mm_RefseqmRNA = NM_178804.3
| Mm_RefseqProtein = NP_848919.3
| Mm_GenLoc_db = mm9
| Mm_GenLoc_chr = 5
| Mm_GenLoc_start = 48374394
| Mm_GenLoc_end = 48697017
| Mm_Uniprot = Q5DTL5
}}


'''Class C β-lactamases''' are a subcategory of β-lactamase enzymes. These enzymes are produced by some bacteria and result in their resistance to a variety of β-lactam antibiotics. β-lactam antibiotics are classified based on their chemical structure which contains a four membered, amide containing ring known as the β-lactam ring. Class C β-lactamases specifically target [http://en.m.wikipedia.org/wiki/Cephalosporin cephalosporin] antibiotics and deactivate their antimicrobial activity by hydrolyzing the [http://en.m.wikipedia.org/wiki/Β-lactam β-lactam ring].
'''Class C β-lactamases''' are a subcategory of β-lactamase enzymes. These enzymes are produced by some bacteria and result in their resistance to a variety of β-lactam antibiotics. β-lactam antibiotics are classified based on their chemical structure which contains a four membered, amide containing ring known as the β-lactam ring. Class C β-lactamases specifically target [http://en.m.wikipedia.org/wiki/Cephalosporin cephalosporin] antibiotics and deactivate their antimicrobial activity by hydrolyzing the [http://en.m.wikipedia.org/wiki/Β-lactam β-lactam ring].
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| EC number ||  
| EC number ||  
|-
|-
| CAS number ||  
| [http://en.wikipedia.org/wiki/CAS_Registry_Number CAS number] || <a class="external text" href="//tools.wmflabs.org/magnustools/cas.php?language=en&amp;cas=9073-60-3&amp;title=">9073-60-3</a>
|-
|-
! style="background: #efefef;" colspan="2" |Databases
! style="background: #efefef;" colspan="2" |Databases
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|}


{{PBB|geneid=2194}}
 


== Function and Mechanism ==
== Function and Mechanism ==
Retrieved from "https://proteopedia.org/Sandbox_Reserved_992"