4yd2: Difference between revisions
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''' | ==Nicked complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate== | ||
<StructureSection load='4yd2' size='340' side='right' caption='[[4yd2]], [[Resolution|resolution]] 2.47Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4yd2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YD2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YD2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ycx|4ycx]], [[4yd1|4yd1]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yd2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yd2 RCSB], [http://www.ebi.ac.uk/pdbsum/4yd2 PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/DPOLM_HUMAN DPOLM_HUMAN]] Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.<ref>PMID:12640116</ref> <ref>PMID:12888504</ref> <ref>PMID:17483519</ref> <ref>PMID:17915942</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: DNA-directed DNA polymerase]] | |||
[[Category: Bebenek, K]] | [[Category: Bebenek, K]] | ||
[[Category: Gosavi, R | [[Category: Gosavi, R A]] | ||
[[Category: Pedersen, L | [[Category: Kunkel, T A]] | ||
[[Category: | [[Category: Moon, A F]] | ||
[[Category: Pedersen, L C]] | |||
[[Category: Dna repair]] | |||
[[Category: Nhej]] | |||
[[Category: Polymerase]] | |||
[[Category: Transferase-dna complex]] | |||
Revision as of 20:14, 5 August 2015
Nicked complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate
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