5ahm: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==IMP-bound form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa==

~~The entry~~ 5ahm is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5ahm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AHM OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AHM FirstGlance].

~~Authors~~: ~~Labesse~~, G., ~~Alexandre~~, T., ~~Gelin~~, M.~~, Haouz, A~~.~~, Munier-Lehmann, H~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5ahl|5ahl]], [[5ahn|5ahn]]</td></tr>

~~Description~~: IMP-~~bound form~~ of the ~~DeltaCBS mutant~~ of ~~IMPDH from Pseudomonas aeruginosa~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ahm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ahm RCSB], [http://www.ebi.ac.uk/pdbsum/5ahm PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]

__TOC__

</StructureSection>

[[Category: IMP dehydrogenase]]

[[Category: Alexandre, T]]

[[Category: Gelin, M]]

[[Category: Haouz, A]]

[[Category: Labesse, G]]

[[Category: Munier-Lehmann, H]]

[[Category: ~~Gelin, M~~]]

[[Category: Allosteric regu nucleotide metabolism]]

[[Category: ~~Haouz, A~~]]

[[Category: Cbs module]]

[[Category: ~~Alexandre, T~~]]

[[Category: Deletion mutant]]

[[Category: Oxidoreductase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==IMP-bound form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa==
+<StructureSection load='5ahm' size='340' side='right' caption='[[5ahm]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
-The entry 5ahm is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5ahm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AHM FirstGlance]. <br>
-Authors: Labesse, G., Alexandre, T., Gelin, M., Haouz, A., Munier-Lehmann, H.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ahl|5ahl]], [[5ahn|5ahn]]</td></tr>
-Description: IMP-bound form of the DeltaCBS mutant of IMPDH from Pseudomonas aeruginosa
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ahm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ahm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ahm RCSB], [http://www.ebi.ac.uk/pdbsum/5ahm PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
+__TOC__
+</StructureSection>
+[[Category: IMP dehydrogenase]]
+[[Category: Alexandre, T]]
+[[Category: Gelin, M]]
+[[Category: Haouz, A]]
 [[Category: Labesse, G]]
 [[Category: Munier-Lehmann, H]]
-[[Category: Gelin, M]]
+[[Category: Allosteric regu nucleotide metabolism]]
-[[Category: Haouz, A]]
+[[Category: Cbs module]]
-[[Category: Alexandre, T]]
+[[Category: Deletion mutant]]
+[[Category: Oxidoreductase]]