Sandbox Reserved 996: Difference between revisions
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For the second and third proposed mechanisms of action, Ectatomin has also been shown to inhibit kinases, specifically protein tyrosine kinase and protein kinase C, and Ca2+ channels. Kinase inhibition would potentially allow Ectatomin to interfere with various components of signal transduction. Calcium channel inhibition would potentially allow Ectatomin to affect physiological processes such as contraction, neurotransmitter release and neuronal activity regulation. | For the second and third proposed mechanisms of action, Ectatomin has also been shown to inhibit kinases, specifically protein tyrosine kinase and protein kinase C, and Ca2+ channels. Kinase inhibition would potentially allow Ectatomin to interfere with various components of signal transduction. Calcium channel inhibition would potentially allow Ectatomin to affect physiological processes such as contraction, neurotransmitter release and neuronal activity regulation. | ||
[[Possible_Ectatomin_Mechanism_2.png|300px|left|thumb| Proposed membrane insertion mechanism (above) and proposed dimerization to form cation channel (below)]] | [[Image:Possible_Ectatomin_Mechanism_2.png|300px|left|thumb| Proposed membrane insertion mechanism (above) and proposed dimerization to form cation channel (below)]] | ||
== Toxicology == | == Toxicology == | ||
