Catalase: Difference between revisions
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<StructureSection load='1gge' size='450' side='right' scene='' caption='E. coli catalase Hpii tetramer showing the heme group, [[1gge]]'> | |||
'''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a <scene name='57/578105/Heme/1'>heme</scene> group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity. | '''Catalase''' (CAT) catalyzes the conversion of hydrogen peroxide to water and oxygen. CAT contains porphyrin-heme Fe group which reacts with the hydrogen peroxide. CAT containing Mn are called pseudocatalase (PCAT). '''Catalase-peroxidase''' (CAT KatG) is a bifunctional enzyme with both catalase and peroxidase activities. CAT KatG cofactor is a <scene name='57/578105/Heme/1'>heme</scene> group. It provides defense against oxidative stress by reducing hydrogen peroxide. Mutations in CAT KatG can cause resistance to the anti-malarial drug isoniazid (INH). '''Catalase-phenol oxidase''' (CATPO) is a heme-containing CAT which shows phenol oxidase activity. | ||
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See more details in [[Ann Taylor/Catalase]] and [[Catalase 2CAG bcce2014]].<br /> | See more details in [[Ann Taylor/Catalase]] and [[Catalase 2CAG bcce2014]].<br /> | ||
See also [[Catalase (Hebrew)]]. | See also [[Catalase (Hebrew)]]. | ||
</StructureSection> | |||
== 3D Structures of catalase == | == 3D Structures of catalase == | ||