4yli: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==CL-K1 trimer==

~~The entry~~ 4yli is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4yli]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLI FirstGlance]. <br>

~~Authors~~: ~~Wallis, R~~.~~, Girija, U~~.V., ~~Gingras, A~~.R., ~~Moody, P~~.C.E., ~~Marshall, J~~.E.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yli RCSB], [http://www.ebi.ac.uk/pdbsum/4yli PDBsum]</span></td></tr>

~~Description~~: CL-~~K1 trimer~~

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Disease ==

[[Category: ~~Girija~~, ~~U.V~~]]

[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Craniofacial-ulnar-renal syndrome. The disease is caused by mutations affecting the gene represented in this entry.

[[Category: ~~Marshall~~, ~~J.E~~]]

== Function ==

[[Category: ~~Gingras~~, ~~A.R~~]]

[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity).

[[Category: Moody, P.C.E]]

__TOC__

</StructureSection>

[[Category: Gingras, A R]]

[[Category: Girija, U V]]

[[Category: Marshall, J E]]

[[Category: Moody, P C.E]]

[[Category: Wallis, R]]

[[Category: C-type carbohydrate-recognition domain]]

[[Category: C-type lectin]]

[[Category: Collectin]]

[[Category: Sugar binding protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==CL-K1 trimer==
+<StructureSection load='4yli' size='340' side='right' caption='[[4yli]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
-The entry 4yli is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4yli]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YLI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YLI FirstGlance]. <br>
-Authors: Wallis, R., Girija, U.V., Gingras, A.R., Moody, P.C.E., Marshall, J.E.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yli FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yli OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yli RCSB], [http://www.ebi.ac.uk/pdbsum/4yli PDBsum]</span></td></tr>
-Description: CL-K1 trimer
+</table>
-[[Category: Unreleased Structures]]
+== Disease ==
-[[Category: Girija, U.V]]
+[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Craniofacial-ulnar-renal syndrome. The disease is caused by mutations affecting the gene represented in this entry.
-[[Category: Marshall, J.E]]
+== Function ==
-[[Category: Gingras, A.R]]
+[[http://www.uniprot.org/uniprot/COL11_HUMAN COL11_HUMAN]] Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity).
-[[Category: Moody, P.C.E]]
+__TOC__
+</StructureSection>
+[[Category: Gingras, A R]]
+[[Category: Girija, U V]]
+[[Category: Marshall, J E]]
+[[Category: Moody, P C.E]]
 [[Category: Wallis, R]]
+[[Category: C-type carbohydrate-recognition domain]]
+[[Category: C-type lectin]]
+[[Category: Collectin]]
+[[Category: Sugar binding protein]]