5ame: Difference between revisions
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==Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond I04-1 fragment screening)== | ==Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond I04-1 fragment screening)== | ||
<StructureSection load='5ame' size='340' side='right' caption='[[5ame]], [[Resolution|resolution]] 1.58Å' scene=''> | <StructureSection load='5ame' size='340' side='right' caption='[[5ame]], [[Resolution|resolution]] 1.58Å' scene=''> | ||
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PW3:4-ACETYL-PIPERAZIN-2-ONE'>PW3</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PW3:4-ACETYL-PIPERAZIN-2-ONE'>PW3</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5amf|5amf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5amf|5amf]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ame FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ame OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ame RCSB], [http://www.ebi.ac.uk/pdbsum/5ame PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ame FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ame OCA], [http://pdbe.org/5ame PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ame RCSB], [http://www.ebi.ac.uk/pdbsum/5ame PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ame ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref> | [[http://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref> | ||
==See Also== | |||
*[[Bromodomain-containing protein|Bromodomain-containing protein]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 09:56, 10 March 2017
Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond I04-1 fragment screening)
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Arrowsmith, C H
- Bountra, C
- Bowkett, D
- Bradley, A
- Brandao-Neto, J
- Brennan, P
- Burgess-Brown, N
- Collins, P
- Cox, O
- Delft, F von
- Douangamath, A
- Edwards, E
- Fairhead, M
- Krojer, T
- Ng, J T
- Pearce, N M
- Strain-Damerell, C
- Talon, R
- Wright, N
- Bromodomain
- Diamond i04-1
- Epigenetic
- Fragmentscreening
- Histone-binding protein
- Sgc
- Structural genomic
- Transcription
