Sandbox Reserved 1059: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 27: | Line 27: | ||
== Relevance == | == Relevance == | ||
Genes that encode for NrdE and NrdF are essential for growth and RR might be an attractive biochemical pathway for antimycobacterial drug discovery. Organisms that depend solely on class 1B RNR could potentially be the essential genes and potential drug targets for treating tuberculosis.<ref>DOI 10.1021/bi400191z</ref> | Genes that encode for NrdE and NrdF are essential for growth and RR might be an attractive biochemical pathway for antimycobacterial drug discovery. Organisms that depend solely on class 1B RNR could potentially be the essential genes and potential drug targets for treating tuberculosis.<ref>DOI 10.1021/bi400191z</ref> | ||
[[Image:Image_7_(1).png|100px|left|thumb|Sequence alignment of NrdH from ''Mycobacterium tuberculosis, Corynebacterium glutamicum, and ''Echerichia coli'''']] | |||