4uhl: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "4uhl" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP== | |||
<StructureSection load='4uhl' size='340' side='right' caption='[[4uhl]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4uhl]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UHL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UHL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=VFV:N-[(1R)-1-(3,4-DIFLUOROBIPHENYL-4-YL)-2-(1H-IMIDAZOL-1-YL)ETHYL]-4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BENZAMIDE'>VFV</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uhi|4uhi]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sterol_14-demethylase Sterol 14-demethylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.70 1.14.13.70] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uhl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uhl OCA], [http://pdbe.org/4uhl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uhl RCSB], [http://www.ebi.ac.uk/pdbsum/4uhl PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CP51A_HUMAN CP51A_HUMAN]] Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Sterol 14-demethylase]] | |||
[[Category: Hargrove, T Y]] | |||
[[Category: Lepesheva, G I]] | |||
[[Category: Wawrzak, Z]] | [[Category: Wawrzak, Z]] | ||
[[Category: | [[Category: Cyp51]] | ||
[[Category: | [[Category: Cytochrome p450]] | ||
[[Category: Cytochrome p450 fold]] | |||
[[Category: Endoplasmic reticulum]] | |||
[[Category: Eukaryotic membrane]] | |||
[[Category: Monooxygenase]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Sterol biosynthesis]] | |||
Revision as of 22:20, 20 June 2016
HUMAN STEROL 14-ALPHA DEMETHYLASE (CYP51) IN COMPLEX WITH VFV IN P1 SPACE GROUP
| ||||||||||||
