4ytb: Difference between revisions
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''' | ==Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln.== | ||
<StructureSection load='4ytb' size='340' side='right' caption='[[4ytb]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ytb]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Porphyromonas_gingivalis Porphyromonas gingivalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YTB FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GLN:GLUTAMINE'>GLN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4yt9|4yt9]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ytb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ytb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ytb RCSB], [http://www.ebi.ac.uk/pdbsum/4ytb PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PAD_PORGI PAD_PORGI]] Deiminates the guanidino group of C-terminal arginine residues on a variety of peptides, including the vasoregulatory peptide-hormone bradykinin, to yield ammonia and a citrulline residue. May promote the growth of the pathogen in the periodontal pocket by producing ammonia, ammonia having a protective effect during acidic cleaning cycles in the mouth.<ref>PMID:10377098</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Porphyromonas gingivalis]] | |||
[[Category: Garcia-Ferrer, I]] | [[Category: Garcia-Ferrer, I]] | ||
[[Category: Gomis-Ruth, F | [[Category: Gomis-Ruth, F X]] | ||
[[Category: Goulas, T]] | [[Category: Goulas, T]] | ||
[[Category: Guevara, T]] | |||
[[Category: Kantyka, T]] | |||
[[Category: Millan, C]] | |||
[[Category: Mizgalska, D]] | |||
[[Category: Mydel, P]] | |||
[[Category: Potempa, B]] | [[Category: Potempa, B]] | ||
[[Category: Potempa, J]] | [[Category: Potempa, J]] | ||
[[Category: Sola, M]] | [[Category: Sola, M]] | ||
[[Category: Sroka, A]] | [[Category: Sroka, A]] | ||
[[Category: Szmigielski, B]] | [[Category: Szmigielski, B]] | ||
[[Category: Uson, I]] | |||
[[Category: Veillard, F]] | |||
[[Category: Citrullination]] | |||
[[Category: Hydrolase]] | |||
[[Category: Peptidylarginine deiminase]] | |||
Revision as of 12:24, 1 July 2015
Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln.
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