Sandbox Reserved 1066: Difference between revisions

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<blockquote></blockquote>{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}

==Your Heading Here (maybe something like 'Structure')==

~~This is a default text for your page '''StephanieShoults/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs.~~

~~You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.~~

= Introduction =

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''Mycobacterium tuberculosis'' very-long-chain fatty acyl-CoA synthetase, also known as FadD13, is unique within its class in regards to its ability to house lipid substrates longer than itself. Most FadD class proteins exist as integral membrane proteins involved in lipid transport into the cell. FadD13 is unique structurally in that it exists as a peripheral protein on the inside of the cell membrane. This feature is key in the mechanistic basis for FadD13's transport of fatty acids of length C24-C26.<ref name="Our Paper">PMID: 22560731</ref>

FadD13 may be important in the virulence of [https://en.wikipedia.org/wiki/Tuberculosis tuberculosis] and has emerged as possible target for therapeutic agents.

FadD13 may be important in the virulence of [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis ''Mycobacterium tuberculosis''], the etiological agent of [https://en.wikipedia.org/wiki/Tuberculosis tuberculosis], and has emerged as possible target for novel therapeutic agents.

= Mechanism =

Sandbox Reserved 1066: Difference between revisions

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 <blockquote></blockquote>{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
 ==Your Heading Here (maybe something like 'Structure')==
 <StructureSection load='3r44' size='340' side='right' caption='Very Long Chain Fatty Acyl CoA Synthetase (FadD13)' scene='69/694232/Opening_scene/1'>
-This is a default text for your page '''StephanieShoults/Sandbox1'''. Click above on '''edit this page''' to modify. Be careful with the &lt; and &gt; signs.
-You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.
 = Introduction =
@@ Line 10: / Line 11: @@
 ''Mycobacterium tuberculosis'' very-long-chain fatty acyl-CoA synthetase, also known as FadD13, is unique within its class in regards to its ability to house lipid substrates longer than itself. Most FadD class proteins exist as integral membrane proteins involved in lipid transport into the cell. FadD13 is unique structurally in that it exists as a peripheral protein on the inside of the cell membrane. This feature is key in the mechanistic basis for FadD13's transport of fatty acids of length C24-C26.<ref name="Our Paper">PMID: 22560731</ref>
-FadD13 may be important in the virulence of [https://en.wikipedia.org/wiki/Tuberculosis tuberculosis] and has emerged as possible target for therapeutic agents.
+FadD13 may be important in the virulence of [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis ''Mycobacterium tuberculosis''], the etiological agent of [https://en.wikipedia.org/wiki/Tuberculosis tuberculosis], and has emerged as possible target for novel therapeutic agents.
 = Mechanism =