GMP synthase: Difference between revisions
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<StructureSection load='2vxo' size='400' side='right' caption='Structure of human GMP synthase dimer complex with xantosine 5-phosphate (stick model) and sulfate (PDB entry [[2vxo]])' scene=''> | <StructureSection load='2vxo' size='400' side='right' caption='Structure of human GMP synthase dimer complex with xantosine 5-phosphate (stick model) and sulfate (PDB entry [[2vxo]])' scene=''> | ||
== Function == | |||
'''GMP synthase''' (GMPS) catalyzes the conversion of xantosine 5’-phosphate, ATP, glutamine and water to glutamate, GMP, AMP and diphosphate. GMPS is active in purine and glutamate metabolism<ref>PMID:24462112</ref>. | |||
== Structural highlights == | |||
==3D structures of GMP synthase== | ==3D structures of GMP synthase== | ||
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[[2iss]] – TmGMPS subunit PDXT + PLP biosynthesis lyase PDXS<br /> | [[2iss]] – TmGMPS subunit PDXT + PLP biosynthesis lyase PDXS<br /> | ||
[[1gpm]] – GMPS + pyrophosphate + AMP – ''Escherichia coli'' | [[1gpm]] – GMPS + pyrophosphate + AMP – ''Escherichia coli'' | ||
== References == | |||
<references/> | |||
</StructureSection> | </StructureSection> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
