Sandbox Reserved 1066: Difference between revisions
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==='''Salicylate synthase (SS)'''=== | |||
Chromate is converted to salicylate synthase by MbtI through an intermediate isochromate, bound to an enzyme . During this reaction, a pyruvate molecule is expelled after the intermediate step (Figure 9). Through inhibition studies, mimics of isochromate were made and bound with MbtI. However, the results did not yield a clear modality for isochromate biding to the active site. Between the two different modalities, two amino acids remained involved in the binding: Arg405 and Tyr385. This illudes to a very flexible binding site<ref name="2a">PMID:23108268</ref>. | |||
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