4z35: Difference between revisions

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'''Unreleased structure'''
==Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-9910539==
 
<StructureSection load='4z35' size='340' side='right' caption='[[4z35]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
The entry 4z35 is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4z35]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z35 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z35 FirstGlance]. <br>
Authors: Chrencik, J.E., Roth, C.B., Terakado, M., Kurata, H., Omi, R., Kihara, Y., Warshaviak, D., Nakade, S., Asmar-Rovira, G., Mileni, M., Mizuno, H., Griffith, M.T., Rodgers, C., Han, G.W., Velasquez, J., Chun, J., Stevens, R.C., Hanson, M.A., GPCR Network (GPCR)
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1WV:(2S)-2,3-DIHYDROXYPROPYL+(7Z)-TETRADEC-7-ENOATE'>1WV</scene>, <scene name='pdbligand=ON9:3-{1-[(2S,3S)-3-(4-ACETYL-3,5-DIMETHOXYPHENYL)-2-(2,3-DIHYDRO-1H-INDEN-2-YLMETHYL)-3-HYDROXYPROPYL]-4-(METHOXYCARBONYL)-1H-PYRROL-3-YL}PROPANOIC+ACID'>ON9</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z36|4z36]], [[4z34|4z34]]</td></tr>
Description: Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO-9910539
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z35 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4z35 RCSB], [http://www.ebi.ac.uk/pdbsum/4z35 PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Chrencik, J.E]]
== Function ==
[[Category: Roth, C.B]]
[[http://www.uniprot.org/uniprot/LPAR1_HUMAN LPAR1_HUMAN]] Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.<ref>PMID:19306925</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Asmar-Rovira, G]]
[[Category: Chrencik, J E]]
[[Category: Chun, J]]
[[Category: GPCR, GPCR Network]]
[[Category: Griffith, M T]]
[[Category: Han, G W]]
[[Category: Hanson, M A]]
[[Category: Kihara, Y]]
[[Category: Kurata, H]]
[[Category: Mileni, M]]
[[Category: Mizuno, H]]
[[Category: Mizuno, H]]
[[Category: Nakade, S]]
[[Category: Omi, R]]
[[Category: Rodgers, C]]
[[Category: Rodgers, C]]
[[Category: Roth, C B]]
[[Category: Stevens, R C]]
[[Category: Terakado, M]]
[[Category: Terakado, M]]
[[Category: Nakade, S]]
[[Category: Velasquez, J]]
[[Category: Chun, J]]
[[Category: Kurata, H]]
[[Category: Stevens, R.C]]
[[Category: Omi, R]]
[[Category: Han, G.W]]
[[Category: Hanson, M.A]]
[[Category: Kihara, Y]]
[[Category: Warshaviak, D]]
[[Category: Warshaviak, D]]
[[Category: Velasquez, J]]
[[Category: Antagonist]]
[[Category: Asmar-Rovira, G]]
[[Category: Compound design]]
[[Category: Gpcr Network (Gpcr)]]
[[Category: Endogenous ligand]]
[[Category: Griffith, M.T]]
[[Category: Gpcr network]]
[[Category: Mileni, M]]
[[Category: Lipid receptor]]
[[Category: Membrane protein]]
[[Category: Polypharmacology]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
Retrieved from "https://proteopedia.org/4z35"