4ydi: Difference between revisions
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==Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17== | |||
<StructureSection load='4ydi' size='340' side='right' caption='[[4ydi]], [[Resolution|resolution]] 3.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ydi]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YDI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YDI FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ydj|4ydj]], [[4ydk|4ydk]], [[4ydl|4ydl]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ydi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ydi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ydi RCSB], [http://www.ebi.ac.uk/pdbsum/4ydi PDBsum]</span></td></tr> | |||
[[ | </table> | ||
[[Category: Kwong, P | == Function == | ||
[[http://www.uniprot.org/uniprot/O55774_9HIV1 O55774_9HIV1]] The envelope glyprotein gp160 precursor down-modulates cell surface CD4 antigen by interacting with it in the endoplasmic reticulum and blocking its transport to the cell surface.[RuleBase:RU004292] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Kwong, P D]] | |||
[[Category: Srivatsan, S]] | [[Category: Srivatsan, S]] | ||
[[Category: Zhou, T]] | [[Category: Zhou, T]] | ||
[[Category: Antibody]] | |||
[[Category: Hiv-1]] | |||
[[Category: Immune system]] | |||
Revision as of 12:47, 3 June 2015
Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17
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