4zeq: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
m Protected "4zeq" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
==Crystal Structure of human BFL-1 in complex with tBid BH3 peptide, Northeast Structural Genomics Consortium Target HX9247==
 
<StructureSection load='4zeq' size='340' side='right' caption='[[4zeq]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
The entry 4zeq is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4zeq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZEQ FirstGlance]. <br>
Authors: Guan, R., Xiao, R., Mao, L., Montelione, G.T., Northeast Structural Genomics Consortium (NESG)
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zeq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zeq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zeq RCSB], [http://www.ebi.ac.uk/pdbsum/4zeq PDBsum]</span></td></tr>
 
</table>
Description: Crystal Structure of human BFL-1 in complex with tBid BH3 peptide, Northeast Structural Genomics Consortium Target HX9247
== Function ==
[[Category: Unreleased Structures]]
[[http://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN]] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). [[http://www.uniprot.org/uniprot/BID_HUMAN BID_HUMAN]] The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.<ref>PMID:14583606</ref> 
[[Category: Northeast Structural Genomics Consortium (Nesg)]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Guan, R]]
[[Category: Mao, L]]
[[Category: Montelione, G T]]
[[Category: Structural genomic]]
[[Category: Xiao, R]]
[[Category: Xiao, R]]
[[Category: Mao, L]]
[[Category: Apoptosis]]
[[Category: Montelione, G.T]]
[[Category: Bcl-2 family]]
[[Category: Guan, R]]
[[Category: Bh3 only]]
[[Category: Complex]]
[[Category: Nesg]]
[[Category: Psi-biology]]
Retrieved from "https://proteopedia.org/4zeq"