4z2a: Difference between revisions
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==Crystal structure of unglycosylated apo human furin @1.89A== | |||
<StructureSection load='4z2a' size='340' side='right' caption='[[4z2a]], [[Resolution|resolution]] 1.89Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4z2a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Z2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Z2A FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1p8j|1p8j]], [[4omc|4omc]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Furin Furin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.75 3.4.21.75] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4z2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4z2a OCA], [http://pdbe.org/4z2a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4z2a RCSB], [http://www.ebi.ac.uk/pdbsum/4z2a PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/FURIN_HUMAN FURIN_HUMAN]] Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.<ref>PMID:7690548</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Furin]] | |||
[[Category: Gampe, R T]] | |||
[[Category: Pearce, K]] | [[Category: Pearce, K]] | ||
[[Category: Reid, R]] | [[Category: Reid, R]] | ||
[[Category: Apo]] | |||
[[Category: Hydrolase]] | |||
[[Category: Serine proteinase]] | |||
[[Category: Unglycosylated]] | |||
Revision as of 19:32, 13 May 2016
Crystal structure of unglycosylated apo human furin @1.89A
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