4zqm: Difference between revisions
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''' | ==Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD== | ||
<StructureSection load='4zqm' size='340' side='right' caption='[[4zqm]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4zqm]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZQM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZQM FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zqn|4zqn]], [[4zqo|4zqo]], [[4zqp|4zqp]], [[4zqr|4zqr]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zqm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zqm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4zqm RCSB], [http://www.ebi.ac.uk/pdbsum/4zqm PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/IMDH_MYCTU IMDH_MYCTU]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Andesrson, W F]] | |||
[[Category: Structural genomic]] | |||
[[Category: Gu, M]] | |||
[[Category: Hedstrom, L]] | |||
[[Category: Joachimiak, A]] | [[Category: Joachimiak, A]] | ||
[[Category: Kavitha, M]] | |||
[[Category: Kim, Y]] | |||
[[Category: Makowska-Grzyska, M]] | [[Category: Makowska-Grzyska, M]] | ||
[[Category: Maltseva, N]] | [[Category: Maltseva, N]] | ||
[[Category: | [[Category: Csgid]] | ||
[[Category: | [[Category: Delta-cb]] | ||
[[Category: | [[Category: Impdh]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis]] | ||
Revision as of 15:33, 17 June 2015
Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with XMP and NAD
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