357d: Difference between revisions
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|PDB= 357d |SIZE=350|CAPTION= <scene name='initialview01'>357d</scene>, resolution 3.500Å | |PDB= 357d |SIZE=350|CAPTION= <scene name='initialview01'>357d</scene>, resolution 3.500Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand= | |LIGAND= <scene name='pdbligand=A:ADENOSINE-5'-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5'-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5'-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SSU:URIDINE-5'-PHOSPHOROTHIOATE'>SSU</scene>, <scene name='pdbligand=U:URIDINE-5'-MONOPHOSPHATE'>U</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=357d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=357d OCA], [http://www.ebi.ac.uk/pdbsum/357d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=357d RCSB]</span> | |||
}} | }} | ||
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[[Category: Moore, P B.]] | [[Category: Moore, P B.]] | ||
[[Category: Steitz, T A.]] | [[Category: Steitz, T A.]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: internal loop]] | [[Category: internal loop]] | ||
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[[Category: u-rna]] | [[Category: u-rna]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:43 2008'' | ||
Revision as of 02:21, 31 March 2008
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| 357d, resolution 3.500Å | |||||||||||||
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| Ligands: | A, C, G, HG, MG, SSU, U | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
3.5 A STRUCTURE OF FRAGMENT I FROM E. COLI 5S RRNA
Overview
Two new RNA structures portray how non-Watson-Crick base pairs and metal ions can produce a unique RNA shape suitable for recognition by proteins. The crystal structures of a 62 nt domain of E. coli 5S ribosomal RNA and a duplex dodecamer encompassing an internal loop E have been determined at 3.0 and 1.5 A, respectively. This loop E region is distorted by three "cross-strand purine stacks" and three novel, water-mediated noncanonical base pairs and stabilized by a four metal ion zipper. These features give its minor groove a unique hydrogen-bonding surface and make the adjacent major groove wide enough to permit recognition by the ribosomal protein L25, which is expected to bind to this surface.
About this Structure
357D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Metals, motifs, and recognition in the crystal structure of a 5S rRNA domain., Correll CC, Freeborn B, Moore PB, Steitz TA, Cell. 1997 Nov 28;91(5):705-12. PMID:9393863 [[Category: ]]
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