4zoj: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)== | |||
<StructureSection load='4zoj' size='340' side='right' caption='[[4zoj]], [[Resolution|resolution]] 1.96Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4zoj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZOJ FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=61L:4-METHYL-2-{[2-METHYL-6-(METHYLSULFANYL)PHENYL]AMINO}BENZOIC+ACID'>61L</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PRP:ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC+ACID'>PRP</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4giu|4giu]], [[3qr9|3qr9]], [[4zof|4zof]], [[4zok|4zok]]</td></tr> | ||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr> | ||
[[Category: Evans, G | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zoj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zoj OCA], [http://pdbe.org/4zoj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zoj RCSB], [http://www.ebi.ac.uk/pdbsum/4zoj PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Anthranilate phosphoribosyltransferase]] | |||
[[Category: Baker, E N]] | |||
[[Category: Evans, G L]] | |||
[[Category: Lott, J S]] | |||
[[Category: Structural genomic]] | |||
[[Category: Complex]] | |||
[[Category: Inhibitor]] | |||
[[Category: Lobenzarit-like analogue]] | |||
[[Category: Magnesium binding]] | |||
[[Category: Phosphoribosylpyrophosphate]] | |||
[[Category: Phosphoribosyltransferase]] | |||
[[Category: Prpp]] | |||
[[Category: Tbsgc]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||
Revision as of 17:03, 15 May 2016
Methylsulfanyl-containing inhibitor bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)
| ||||||||||||
