3b2v: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
|PDB= 3b2v |SIZE=350|CAPTION= <scene name='initialview01'>3b2v</scene>, resolution 3.30Å | |PDB= 3b2v |SIZE=350|CAPTION= <scene name='initialview01'>3b2v</scene>, resolution 3.30Å | ||
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+3281'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+3282'>AC2</scene>, <scene name='pdbsite=AC3:Ndg+Binding+Site+For+Residue+A+3371'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+A+3891'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+A+4201'>AC5</scene> and <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+A+5041'>AC6</scene> | |SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+3281'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+3282'>AC2</scene>, <scene name='pdbsite=AC3:Ndg+Binding+Site+For+Residue+A+3371'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+A+3891'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+A+4201'>AC5</scene> and <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+A+5041'>AC6</scene> | ||
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> | |LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> | ||
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span> | ||
|GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EGFR, ERBB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EGFR, ERBB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
|DOMAIN= | |||
|RELATEDENTRY=[[3b2u|3B2U]] | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b2v OCA], [http://www.ebi.ac.uk/pdbsum/3b2v PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b2v RCSB]</span> | |||
}} | }} | ||
'''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8''' | '''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8''' | ||
==Disease== | |||
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]] | |||
==About this Structure== | ==About this Structure== | ||
| Line 20: | Line 26: | ||
[[Category: Kussie, P.]] | [[Category: Kussie, P.]] | ||
[[Category: Li, S.]] | [[Category: Li, S.]] | ||
[[Category: alternative splicing]] | [[Category: alternative splicing]] | ||
[[Category: anti-oncogene]] | [[Category: anti-oncogene]] | ||
[[Category: antigen:antibody complex]] | |||
[[Category: antitumor]] | |||
[[Category: atp-binding]] | [[Category: atp-binding]] | ||
[[Category: cell cycle]] | [[Category: cell cycle]] | ||
[[Category: cell surface receptor | [[Category: cell surface receptor]] | ||
[[Category: disease mutation]] | [[Category: disease mutation]] | ||
[[Category: drug]] | |||
[[Category: fab fragment]] | |||
[[Category: glycoprotein]] | |||
[[Category: immune system/transferase complex]] | [[Category: immune system/transferase complex]] | ||
[[Category: kinase]] | [[Category: kinase]] | ||
| Line 39: | Line 49: | ||
[[Category: ubl conjugation]] | [[Category: ubl conjugation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:22:31 2008'' | ||
