5bpw: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain==

~~The entry~~ 5bpw is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5bpw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BPW FirstGlance]. <br>

~~Authors~~: ~~Kulkarni~~, K., ~~Yang~~, J.~~, Zhang, Z~~.~~, Barford, D~~.

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bpw RCSB], [http://www.ebi.ac.uk/pdbsum/5bpw PDBsum]</span></td></tr>

</table>

~~Description~~: ~~Atomic~~-~~resolution structures~~ of the APC/C ~~subunits Apc4~~ and the ~~Apc5 N~~-~~terminal domain~~

== Function ==

[[Category: ~~Unreleased Structures~~]]

[[http://www.uniprot.org/uniprot/APC4_HUMAN APC4_HUMAN]] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Barford, D]]

[[Category: Kulkarni, K]]

[[Category: Yang, J]]

[[Category: Zhang, Z]]

[[Category: ~~Yang, J~~]]

[[Category: Anaphase promoting complex]]

[[Category: ~~Kulkarni, K~~]]

[[Category: Apc/c]]

[[Category: ~~Barford, D~~]]

[[Category: Apc4]]

[[Category: Cell cycle]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain==
+<StructureSection load='5bpw' size='340' side='right' caption='[[5bpw]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
-The entry 5bpw is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5bpw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BPW FirstGlance]. <br>
-Authors: Kulkarni, K., Yang, J., Zhang, Z., Barford, D.
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bpw RCSB], [http://www.ebi.ac.uk/pdbsum/5bpw PDBsum]</span></td></tr>
+</table>
-Description: Atomic-resolution structures of the APC/C subunits Apc4 and the Apc5 N-terminal domain
+== Function ==
-[[Category: Unreleased Structures]]
+[[http://www.uniprot.org/uniprot/APC4_HUMAN APC4_HUMAN]] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Barford, D]]
+[[Category: Kulkarni, K]]
+[[Category: Yang, J]]
 [[Category: Zhang, Z]]
-[[Category: Yang, J]]
+[[Category: Anaphase promoting complex]]
-[[Category: Kulkarni, K]]
+[[Category: Apc/c]]
-[[Category: Barford, D]]
+[[Category: Apc4]]
+[[Category: Cell cycle]]