5a57: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT==

~~The entry~~ 5a57 is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5a57]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A57 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A57 FirstGlance].

~~Authors~~: ~~Gregg, K~~.J.~~, Suits, M~~.D.L., ~~Deng~~, L., ~~Vocadlo~~, ~~D.J.~~, ~~Boraston~~, ~~A.B.~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=5G0:(Z)-[(3R,4R,5R,6R)-3-ACETAMIDO-6-(HYDROXYMETHYL)-4,5-BIS(OXIDANYL)OXAN-2-YLIDENE]AMINO]+N-PHENYLCARBAMATE'>5G0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5a55|5a55]], [[5a56|5a56]], [[5a58|5a58]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr>

~~Description~~: ~~The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a57 RCSB], [http://www.ebi.ac.uk/pdbsum/5a57 PDBsum]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

[[~~Category~~: ~~Suits~~, M.D.L]]

== Function ==

[[~~Category~~: ~~Gregg, K~~.J]]

[[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity).

[[Category: Boraston, A.B]]

__TOC__

</StructureSection>

[[Category: Boraston, A B]]

[[Category: Deng, L]]

[[Category: Vocadlo, D.J]]

[[Category: Gregg, K J]]

[[Category: Suits, M D.L]]

[[Category: Vocadlo, D J]]

[[Category: Endo-beta-n-acetylgalactosaminidase]]

[[Category: Gh101]]

[[Category: Glycoside hydrolase family 101]]

[[Category: Hydrolase]]

[[Category: Mucin degradation]]

[[Category: T-antigen]]

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-'''Unreleased structure'''
+==The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT==
+<StructureSection load='5a57' size='340' side='right' caption='[[5a57]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
-The entry 5a57 is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5a57]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A57 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A57 FirstGlance]. <br>
-Authors: Gregg, K.J., Suits, M.D.L., Deng, L., Vocadlo, D.J., Boraston, A.B.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5G0:(Z)-[(3R,4R,5R,6R)-3-ACETAMIDO-6-(HYDROXYMETHYL)-4,5-BIS(OXIDANYL)OXAN-2-YLIDENE]AMINO]+N-PHENYLCARBAMATE'>5G0</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a55|5a55]], [[5a56|5a56]], [[5a58|5a58]], [[5a59|5a59]], [[5a5a|5a5a]]</td></tr>
-Description: The structure of GH101 from Streptococcus pneumoniae TIGR4 in complex with PUGT
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a57 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a57 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a57 RCSB], [http://www.ebi.ac.uk/pdbsum/5a57 PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Suits, M.D.L]]
+== Function ==
-[[Category: Gregg, K.J]]
+[[http://www.uniprot.org/uniprot/GH101_STRPN GH101_STRPN]] Is involved in the breakdown of mucin-type O-linked glycans. Specifically removes the T-antigen disaccharide (Gal-beta-1,3-GalNAc-alpha) from extracellular host glycoproteins. Is representative of a broadly important class of virulence factors (By similarity).
-[[Category: Boraston, A.B]]
+__TOC__
+</StructureSection>
+[[Category: Boraston, A B]]
 [[Category: Deng, L]]
-[[Category: Vocadlo, D.J]]
+[[Category: Gregg, K J]]
+[[Category: Suits, M D.L]]
+[[Category: Vocadlo, D J]]
+[[Category: Endo-beta-n-acetylgalactosaminidase]]
+[[Category: Gh101]]
+[[Category: Glycoside hydrolase family 101]]
+[[Category: Hydrolase]]
+[[Category: Mucin degradation]]
+[[Category: T-antigen]]