Netrin receptor: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='4urt' size='340' side='right' caption='Human netrin receptor DCC fibronectin type V-VI domains complex with neutrin-1 (PDB code 4urt)' scene=''> '''Netrin rece... |
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<StructureSection load='4urt' size='340' side='right' caption='Glycosylated human netrin receptor DCC fibronectin type V-VI domains (green) complex with neutrin-1 (grey), sulfate, Ca+2 and Cl-1 ions (PDB code [[4urt]])' scene=''> | |||
<StructureSection load='4urt' size='340' side='right' caption=' | |||
'''Netrin receptors''' are cell surface proteins which bind netrins. Netrins direct cell and axon migration during development. Netrin attraction is mediated through DCC (Deleted in Colorectal Cancer) receptors while netrin repulsion is mediated through the UNC-5 receptor. | '''Netrin receptors''' are cell surface proteins which bind netrins. Netrins direct cell and axon migration during development. Netrin attraction is mediated through DCC (Deleted in Colorectal Cancer) receptors while netrin repulsion is mediated through the UNC-5 receptor. | ||