5a66: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of AtTTM3 in complex with tripolyphosphate and manganese ion (form A)==

~~The entry~~ 5a66 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5a66]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A66 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A66 FirstGlance].

~~Authors~~: ~~Martinez~~, J., ~~Truffault~~, V., ~~Hothorn, M~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a65|5a65]], [[5a67|5a67]], [[5a68|5a68]]</td></tr>

~~Description~~: ~~Crystal structure~~ of ~~AtTTM3~~ in ~~complex with tripolyphosphate~~ and ~~manganese ion (form A)~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a66 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a66 RCSB], [http://www.ebi.ac.uk/pdbsum/5a66 PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TTM3_ARATH TTM3_ARATH]] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity.<ref>PMID:24004165</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Hothorn, M]]

[[Category: Martinez, J]]

[[Category: Truffault, V]]

[[Category: ~~Hothorn, M~~]]

[[Category: Hydrolase]]

[[Category: Inorganic polyphosphate]]

[[Category: Triphosphate tunnel metalloenzyme]]

[[Category: Tripolyphosphate]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of AtTTM3 in complex with tripolyphosphate and manganese ion (form A)==
+<StructureSection load='5a66' size='340' side='right' caption='[[5a66]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-The entry 5a66 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5a66]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A66 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A66 FirstGlance]. <br>
-Authors: Martinez, J., Truffault, V., Hothorn, M.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a65|5a65]], [[5a67|5a67]], [[5a68|5a68]]</td></tr>
-Description: Crystal structure of AtTTM3 in complex with tripolyphosphate and manganese ion (form A)
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a66 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5a66 RCSB], [http://www.ebi.ac.uk/pdbsum/5a66 PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TTM3_ARATH TTM3_ARATH]] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity.<ref>PMID:24004165</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Hothorn, M]]
 [[Category: Martinez, J]]
 [[Category: Truffault, V]]
-[[Category: Hothorn, M]]
+[[Category: Hydrolase]]
+[[Category: Inorganic polyphosphate]]
+[[Category: Triphosphate tunnel metalloenzyme]]
+[[Category: Tripolyphosphate]]