5c7n: Difference between revisions
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''' | ==Crystal structure of the human BRPF1 bromodomain in complex with Bromosporine== | ||
<StructureSection load='5c7n' size='340' side='right' caption='[[5c7n]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5c7n]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C7N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C7N FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMF:BROMOSPORINE'>BMF</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c7n OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5c7n RCSB], [http://www.ebi.ac.uk/pdbsum/5c7n PDBsum]</span></td></tr> | |||
</table> | |||
[[ | == Function == | ||
[[http://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN]] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caflisch, A]] | [[Category: Caflisch, A]] | ||
[[Category: Zhu, J]] | [[Category: Zhu, J]] | ||
[[Category: Bromodomain and phd finger-containing protein 1]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Transferase]] | |||
Revision as of 14:57, 8 July 2015
Crystal structure of the human BRPF1 bromodomain in complex with Bromosporine
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