Haptoglobin receptor: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='3szk' size='340' side='right' caption='IsdH NEAT-3 domain complex with hemoglobin subunits α,β (PDB code 3szk)' scene=''> '''Haptoglobin receptor''' (IsdH) i... |
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<StructureSection load='3szk' size='340' side='right' caption='IsdH NEAT-3 domain (pink and cyan) complex with heme-containing hemoglobin subunits α (grey and yellow) and β (green and magenta) (PDB code [[3szk]])' scene=''> | |||
<StructureSection load='3szk' size='340' side='right' caption='IsdH NEAT-3 domain complex with hemoglobin subunits α | |||
'''Haptoglobin receptor''' (IsdH) is part of the iron-regulated surface determinant system that captures heme from the host hemoproteins. IsdH binds haptoglobin (Hp) which removes hemoglobin (Hb) from the blood by forming Hp-Hb complex. IsdH contains multiple '''NEAT''' (Near Transporter) domains which bind proteins and heme. For more details see [[Molecular Playground/Hemoglobin-Haptoglobin Complex]]. | '''Haptoglobin receptor''' (IsdH) is part of the iron-regulated surface determinant system that captures heme from the host hemoproteins. IsdH binds haptoglobin (Hp) which removes hemoglobin (Hb) from the blood by forming Hp-Hb complex. IsdH contains multiple '''NEAT''' (Near Transporter) domains which bind proteins and heme. For more details see [[Molecular Playground/Hemoglobin-Haptoglobin Complex]]. | ||