452d: Difference between revisions
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|PDB= 452d |SIZE=350|CAPTION= <scene name='initialview01'>452d</scene>, resolution 1.6Å | |PDB= 452d |SIZE=350|CAPTION= <scene name='initialview01'>452d</scene>, resolution 1.6Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=9AD:9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>9AD</scene> | |LIGAND= <scene name='pdbligand=9AD:9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE'>9AD</scene>, <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=452d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=452d OCA], [http://www.ebi.ac.uk/pdbsum/452d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=452d RCSB]</span> | |||
}} | }} | ||
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[[Category: Thorpe, J H.]] | [[Category: Thorpe, J H.]] | ||
[[Category: Todd, A K.]] | [[Category: Todd, A K.]] | ||
[[Category: groove binding]] | [[Category: groove binding]] | ||
[[Category: intercalation]] | [[Category: intercalation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:37:23 2008'' | ||
Revision as of 02:37, 31 March 2008
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| 452d, resolution 1.6Å | |||||||||||||
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| Ligands: | 9AD, DA, DC, DG, DT, MPD | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
ACRIDINE BINDING TO DNA
About this Structure
452D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution., Todd AK, Adams A, Thorpe JH, Denny WA, Wakelin LP, Cardin CJ, J Med Chem. 1999 Feb 25;42(4):536-40. PMID:10052960
Page seeded by OCA on Mon Mar 31 05:37:23 2008
