5cfb: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine==

~~The entry~~ 5cfb is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5cfb]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CFB FirstGlance]. <br>

~~Authors~~: ~~Shaffer~~, P.L., ~~Huang~~, X., ~~Chen, H~~.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SY9:STRYCHNINE'>SY9</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cfb OCA], [http://pdbe.org/5cfb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cfb RCSB], [http://www.ebi.ac.uk/pdbsum/5cfb PDBsum]</span></td></tr>

~~Description~~: ~~Crystal Structure~~ of ~~Human Glycine Receptor alpha-3 Bound~~ to ~~Strychnine~~

</table>

[[Category: ~~Unreleased Structures~~]]

== Function ==

[[http://www.uniprot.org/uniprot/GLRA3_HUMAN GLRA3_HUMAN]] The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

__TOC__

</StructureSection>

[[Category: Chen, H]]

[[Category: Huang, X]]

[[Category: ~~Chen~~, H]]

[[Category: Shaffer, P L]]

[[Category: ~~Shaffer, P.L~~]]

[[Category: Cys-loop receptor]]

[[Category: Ligand-gated ion channel]]

[[Category: Membrane protein]]

[[Category: Neurotransmitter receptor]]

[[Category: Transport protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine==
+<StructureSection load='5cfb' size='340' side='right' caption='[[5cfb]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
-The entry 5cfb is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5cfb]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CFB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CFB FirstGlance]. <br>
-Authors: Shaffer, P.L., Huang, X., Chen, H.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SY9:STRYCHNINE'>SY9</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cfb OCA], [http://pdbe.org/5cfb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cfb RCSB], [http://www.ebi.ac.uk/pdbsum/5cfb PDBsum]</span></td></tr>
-Description: Crystal Structure of Human Glycine Receptor alpha-3 Bound to Strychnine
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
+[[http://www.uniprot.org/uniprot/GLRA3_HUMAN GLRA3_HUMAN]] The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).
+__TOC__
+</StructureSection>
+[[Category: Chen, H]]
 [[Category: Huang, X]]
-[[Category: Chen, H]]
+[[Category: Shaffer, P L]]
-[[Category: Shaffer, P.L]]
+[[Category: Cys-loop receptor]]
+[[Category: Ligand-gated ion channel]]
+[[Category: Membrane protein]]
+[[Category: Neurotransmitter receptor]]
+[[Category: Transport protein]]