Core-binding factor: Difference between revisions
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Michal Harel (talk | contribs) New page: <StructureSection load='1h9d' size='340' side='right' caption='Human CBFα runt domain complex with CBFβ heterodimerization domain and DNA (PDB code 1h9d)' scene=''> '''Core-binding ... |
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<StructureSection load='1h9d' size='340' side='right' caption='Human CBFα runt domain (grey and pink) complex with CBFβ heterodimerization domain (green and yellow) and DNA (PDB code [[1h9d]])' scene=''> | |||
<StructureSection load='1h9d' size='340' side='right' caption='Human CBFα runt domain complex with CBFβ heterodimerization domain and DNA (PDB code [[1h9d]])' scene=''> | |||
'''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of α chain which binds DNA and a regulatory β chain. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. CBF α contains a DNA-binding runt domain (residues 50-177). | '''Core-binding factor''' (CBF) is a heterodimeric transcription factor which is composed of α chain which binds DNA and a regulatory β chain. CBF binds to various enhancers and promoters including murine leukemia virus and polyomavirus enhancer. CBF α contains a DNA-binding runt domain (residues 50-177). | ||
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*Core-binding factor | *Core-binding factor α | ||
**[[1ean]], [[1ljm]] – hCBFα runt domain - human<br /> | **[[1ean]], [[1ljm]] – hCBFα runt domain - human<br /> | ||
