4rsn: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of the E267V mutant of cytochrome P450 BM3==

~~The entry~~ 4rsn is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4rsn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSN OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RSN FirstGlance].

~~Authors~~: ~~Zhou~~, W.H., ~~Zhang~~, A.L., ~~Zhang~~, T., ~~Ren, X~~.K., ~~Yorke~~, J.A., Taylor, A., Wong, L.-L.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[3hf2|3hf2]], [[3m4v|3m4v]]</td></tr>

~~Description: Crystal structure of the E267V mutant of cytochrome P450 BM3~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsn OCA], [http://pdbe.org/4rsn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rsn RCSB], [http://www.ebi.ac.uk/pdbsum/4rsn PDBsum]</td></tr>

[[Category: Zhang, A.L]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

__TOC__

</StructureSection>

[[Category: Unspecific monooxygenase]]

[[Category: Ren, X K]]

[[Category: Taylor, A]]

[[Category: Wong, L L]]

[[Category: Yorke, J A]]

[[Category: Zhang, A L]]

[[Category: Zhang, T]]

[[Category: ~~Yorke~~, ~~J.A~~]]

[[Category: Zhou, W H]]

[[Category: ~~Ren, X.K]]~~

[[Category: Bifunctional p-450/nadph-p450 reductase]]

~~[[Category: Taylor, A~~]]

[[Category: Heme domain]]

[[Category: ~~Wong, L.-L~~]]

[[Category: Oxidoreductase]]

[[Category: ~~Zhou, W.H~~]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the E267V mutant of cytochrome P450 BM3==
+<StructureSection load='4rsn' size='340' side='right' caption='[[4rsn]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-The entry 4rsn is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rsn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RSN FirstGlance]. <br>
-Authors: Zhou, W.H., Zhang, A.L., Zhang, T., Ren, X.K., Yorke, J.A., Taylor, A., Wong, L.-L.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hf2|3hf2]], [[3m4v|3m4v]]</td></tr>
-Description: Crystal structure of the E267V mutant of cytochrome P450 BM3
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Unspecific_monooxygenase Unspecific monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.14.1 1.14.14.1] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rsn OCA], [http://pdbe.org/4rsn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rsn RCSB], [http://www.ebi.ac.uk/pdbsum/4rsn PDBsum]</span></td></tr>
-[[Category: Zhang, A.L]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CPXB_BACME CPXB_BACME]] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.
+__TOC__
+</StructureSection>
+[[Category: Unspecific monooxygenase]]
+[[Category: Ren, X K]]
+[[Category: Taylor, A]]
+[[Category: Wong, L L]]
+[[Category: Yorke, J A]]
+[[Category: Zhang, A L]]
 [[Category: Zhang, T]]
-[[Category: Yorke, J.A]]
+[[Category: Zhou, W H]]
-[[Category: Ren, X.K]]
+[[Category: Bifunctional p-450/nadph-p450 reductase]]
-[[Category: Taylor, A]]
+[[Category: Heme domain]]
-[[Category: Wong, L.-L]]
+[[Category: Oxidoreductase]]
-[[Category: Zhou, W.H]]